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The Center for Translational Injury Research is a part of The University of Texas Health Science Center at Houston.

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PROMMTT Publications

  1. Rahbar MH, Fox EE, del Junco DJ, Cotton BA, Podbielski JM, Matijevic N, Cohen MJ, Schreiber MA, Zhang J, Mirhaji P, Duran SJ, Reynolds RJ, Benjamin-Garner R, Holcomb JB, PROMMTT Investigators. Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study. Resuscitation. 2012 Apr;83(4):459-64. PMID: 22001613. PMCID: 3303947. Read More

  2. Rahbar MH, Huang H, Ning J, del Junco DJ, Fox EE, Holcomb JB on behalf of the PROMMTT Study Group. A latent class model for defining massive hemorrhage. Joint Statistical Meetings Proceedings, Statistics in Epidemiology Section. 2012; Alexandria, VA: American Statistical Association. 3252-3264.

  3. Callcut RA, Cotton BA, Muskat P, Fox EE, Wade CE, Holcomb JB, Schreiber MA, Rahbar MH, Cohen MJ, Knudson MM, Brasel KJ, Bulger EM, Del Junco DJ, Myers JG, Alarcon LH, Robinson BR; PROMMTT Study Group. Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg. 2013 Jan;74(1):59-65, 67-8; discussion 66-7. PMID: 23271078. Read More

  4. Holcomb JB, del Junco DJ, Fox EE, Wade CE, Cohen MJ, Schreiber MA, Alarcon LH, Bai Y, Brasel KJ, Bulger EM, Cotton BA, Matijevic N, Muskat P, Myers JG, Phelan HA, White CE, Zhang J, Rahbar MH; PROMMTT Study Group. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg. 2013 Feb;148(2):127-36. PMID: 23560283. Read More

  5. Holcomb JB, Fox EE, Wade CE; PROMMTT Study Group. The PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S1-2. PMID: 23778505. Read More

  6. del Junco DJ, Fox EE, Camp EA, Rahbar MH, Holcomb JB; PROMMTT Study. Seven deadly sins in trauma outcomes research: An epidemiologic post mortem for major causes of bias. J Trauma Acute Care Surg. 2013 Jul;75(1 Suppl 1):S97-S103. PMID: 23778519. Read More

  7. Fox EE, Bulger EM, Dickerson AS, del Junco DJ, Klotz P, Podbielski J, Matijevic N, Brasel KJ, Holcomb JB, Schreiber MA, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, Wade CE, Rahbar MH, on behalf of the PROMMTT Study Group. Waiver of consent in non-interventional, observational emergency research: the PROMMTT experience. J Trauma Acute Care Surg. 2013;75:S3-S8. PMCID: PMC3744180. Read More

  8. Trickey AW, Fox EE, del Junco DJ, Ning J, Holcomb JB, Brasel KJ, Cohen MJ, Schreiber MA, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Muskat P, Cotton BA, Wade CE, Rahbar MH, on behalf of the PROMMTT Study Group. The impact of missing trauma data on predicting massive transfusion. J Trauma Acute Care Surg. 2013;75:S68-S74. PMID: 23778514 Read More

  9. Hampton DA, Fabricant LJ, Differding J, Diggs B, Underwood S, De La Cruz D, Holcomb JB, Brasel KJ, Cohen MJ, Fox EE, Alarcon LH, Rahbar MH, Phelan HA, Bulger EM, Muskat P, Myers JG, del Junco DJ, Wade CE, Cotton BA, Schreiber MA, on behalf of the PROMMTT study group. Prehospital intravenous fluid is associated with increased survival in trauma patients. J Trauma Acute Care Surg. 2013;75:S9-S15. PMID: 23778518 Read More

  10. Hubbard A, Munoz ID, Decker A, Holcomb JB, Schreiber MA, Bulger EM, Brasel KJ, Fox EE, del Junco DJ, Wade CE, Rahbar MH, Cotton BA, Phelan HA, Myers JG, Alarcon LH, Muskat P, Cohen MJ, on behalf of the PROMMTT study group. Time-Dependent Prediction and Evaluation of Variable Importance Using SuperLearning in High Dimensional Clinical Data. J Trauma Acute Care Surg. 2013;75:S53-S60. PMCID:PMC3744063 Read More

  11. Barbosa RR, Rowell SE, Fox EE, Holcomb JB, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Brasel KJ, Muskat PC, del Junco DJ, Cotton BA, Wade CE, Rahbar MH, Cohen MJ, Schreiber MA, on behalf of the PROMMTT Study Group. Increasing time to operation is associated with decreased survival in patients with a positive FAST exam requiring emergent laparotomy. J Trauma Acute Care Surg. 2013;75:S48-S52. PMCID: PMC3744056 Read More

  12. Rahbar E, Fox EE, del Junco DJ, Harvin JA, Holcomb JB, Wade CE, Schreiber MA, Rahbar MH, Bulger EM, Phelan HA, Brasel KJ, Alarcon LH, Myers JG, Cohen MJ, Muskat P, Cotton BA, on behalf of the PROMMTT Study Group. Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PRospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study. J Trauma Acute Care Surg. 2013;75:S16-S23. PMCID: PMC3744217 Read More

  13. Fuchs PA, del Junco DJ, Fox EE, Holcomb JB, Rahbar MH, Wade CA, Alarcon LH, Brasel KJ, Bulger EM, Cohen MJ, Myers JG, Muskat P, Phelan HA, Schreiber MA, Cotton BA, on behalf of the PROMMTT Study Group. Purposeful Variable Selection and Stratification to Impute Missing FAST Data in Trauma Research. J Trauma Acute Care Surg. 2013;75:S75-S81. PMCID: PMC3744188 Read More

  14. Cohen MJ, Kutcher M, Redick B, Nelson M, Call M, Knudson MM, Schreiber MA, Bulger EM, Muskat P, Alarcon LH, Myers JG, Rahbar MH, Brasel KJ, Phelan HA, del Junco DJ, Fox EE, Wade CE, Holcomb JB, Cotton BA, Matijevic N, on behalf of the PROMMTT Study Group. Clinical and mechanistic drivers of acute traumatic coagulopathy. J Trauma Acute Care Surg. 2013;75:S40-S47. PMCID:PMC3755603 Read More

  15. Wade CE, del Junco DJ, Fox EE, Cotton BA, Cohen MJ, Muskat P, Schreiber MA, Rahbar MH, Sauer M, Brasel KJ, Bulger EM, Myers JG, Phelan HA, Alarcon LH, and Holcomb JB, on behalf of the PROMMTT Study Group. Do Not Resuscitate Orders in Trauma Patients May Bias Mortality-Based Effect Estimates: an evaluation utilizing the PROMMTT study. J Trauma Acute Care Surg.2013;75:S89-S96. PMCID: PMC3744055 Read More

  16. Robinson BRH, Cotton BA, Pritts TA, Branson R, Holcomb JB, Muskat PC, Fox EE, Wade CE, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Rahbar MH, Callcut RA, on behalf of the PROMMTT Study Group. Application of the Berlin definition in PROMMTT patients: The impact of resuscitation on the incidence of hypoxemia. J Trauma Acute Care Surg. 2013;75:S61-S67. PMCID:PMC3744064 Read More

  17. Holcomb JB, Fox EE, Zhang X, White N, Wade CE, Cotton BA, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Muskat P, Rahbar MH, on behalf of the PROMMTT Study Group. Cryoprecipitate use in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study. J Trauma Acute Care Surg. 2013;75:S31-S39. PMCID: PMC3736696 Read More

  18. Rahbar MH, del Junco DJ, Huang H, Ning J, Fox EE, Zhang X, Schreiber MA, Brasel KJ, Bulger EM, Wade CE, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, White CE, Holcomb JB, on behalf of the PROMMTT Study Group. A latent class model for defining severe hemorrhage: Experience from the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study. J Trauma Acute Care Surg. 2013;75:S82-88. PMCID: PMC3744183 Read More

  19. del Junco DJ, Holcomb JB, Fox EE, Brasel KJ, Phelan HA, Bulger EM, Schreiber MA, Muskat P, Alarcon LH, Cohen MJ, Cotton BA, Wade CE, Myers JG, and Rahbar MH, on behalf of the PROMMTT Study Group. Resuscitate early with plasma and platelets or balance blood products gradually: Findings from the Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT). J Trauma Acute Care Surg. 2013;75:S24-S30. PMCID:PMC3744122 Read More

Other Relevant Publications

  1. Borgman MA, Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, Sebesta J, Jenkins D, Wade CE, Holcomb JB. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007 Oct;63(4):805-13. Read More
     
  2. Duchesne JC, Hunt JP, Wahl G, Marr AB, Wang YZ, Weintraub SE, Wright MJ, McSwain NE Jr. Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years? Trauma. 2008 Aug;65(2):272-6. Read More
     
  3. Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, Cocanour CS, Balldin BC, McKinley BA. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma. 2007 Jan;62(1):112-9. Read More
     
  4. Gunter OL Jr, Au BK, Isbell JM, Mowery NT, Young PP, Cotton BA. Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival. J Trauma. 2008 Sep;65(3):527-34. Read More
     
  5. Hess JR, Dutton RB, Holcomb JB, Scalea TM. Giving plasma at a 1:1 ratio with red cells in resuscitation: who might benefit? Transfusion. 2008 Aug;48(8):1763-5.Holcomb JB, Wade CE, Michalek JE, Chisholm GB, Zarzabal LA, Schreiber MA,Gonzalez EA, Pomper GJ, Perkins JG, Spinella PC, Williams KL, Park MS. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008 Sep;248(3):447-58. Read More
     
  6. Holcomb JB, Wade CE, Michalek JE, Chisholm GB, Zarzabal LA, Schreiber MA, Gonzalez EA, Pomper GJ, Perkins JG, Spinella PC, Williams KL, Park MS. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008 Sep;248(3):447-58. Read More
     
  7. Kashuk JL, Moore EE, Johnson JL, Haenel J, Wilson M, Moore JB, Cothren CC, Biffl WL, Banerjee A, Sauaia A. Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer? J Trauma. 2008 Aug;65(2):261-70. Read More
     
  8. Maegele M, Lefering R, Paffrath T, Tjardes T, Simanski C, Bouillon B; Working Group on Polytrauma of the German Society of Trauma Surgery (DGU). Red-blood-cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiple injury: a retrospective analysis from the Trauma Registry of the Deutsche Gesellschaft für Unfallchirurgie. Vox Sang. 2008 Aug;95(2):112-9. Read More
     
  9. Moore FA, Nelson T, McKinley BA, Moore EE, Nathens AB, Rhee P, Puyana JC, Beilman GJ, Cohn SM; StO2 Study Group. Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients? Am J Surg. 2008 Dec;196(6):948-58. Read More
     
  10. Scalea TM, Bochicchio KM, Lumpkins K, Hess JR, Dutton R, Pyle A, Bochicchio GV. Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients. Ann Surg. 2008 Oct;248(4):578-84. Read More
     
  11. Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE; Inflammation the Host Response to Injury Investigators. An FFP:PRBC transfusion ratio ≥1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma. 2008 Nov;65(5):986-93. Read More
     
  12. Spinella PC, Perkins JG, Grathwohl KW, Beekley AC, Niles SE, McLaughlin DF, Wade CE, Holcomb JB. Effect of plasma and red blood cell transfusions on survival in patients with combat related traumatic injuries. J Trauma. 2008 Feb;64(2 Suppl):S69-77. Read More
     
  13. Teixeira PG, Inaba K, Shulman I, Salim A, Demetriades D, Brown C, Browder T, Green D, Rhee P. Impact of plasma transfusion in massively transfused trauma patients. J Trauma. 2009 Mar;66(3):693-7. Read More

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